BRIEF DESCRIPTION OF THE ORGANIZATION
The Laboratory of Nanobioengineering Research managed by Prof. Josep Samitier is situated in the Barcelona Science Park (PCB) and earmarked to become a pioneering research centre in biomedical engineering on nanometric scale. The Nanobioengineering research group comprises a truly multidisciplinary team of 40 researchers coming from very diverse backgrounds (chemistry, physics, material science, microelectronics, electronic engineering, pharmacy, and molecular biology) who work together to apply nano and biotechnology methods to create and deliver successfully biomedical engineering projects and devices. Projects carried out in the lab involve interdisciplinary research that aims to integrate basic research and clinical and industrial applications. The Nanobioengineering lab highly-trained and skilled staff has access to diverse equipment to carry out the characterisation of nanobiosensors through electrochemistry principles (impedance spectroscopy, voltammetry), as well as other complementary techniques such as AFM and surface plasmon resonance.
The laboratory also has access to powerful technological facilities which, in addition to the usual scientific services of the PCB (culture rooms, characterization services), include the Nanotechnology Platform, which offers services such as nano-manufacturing, nano-manipulation and the analysis and characterization of nanotechnologies using such techniques as focused ion beam lithography, nanoimprint lithography, hot embossing lithography, polymer processing and photolithography, chemical wet etching, e-beam evaporation, high-resolution scanning electron microscopy, scanning near-field optical microscopy, atomic force microscopy, molecular force probe, white light interferometric profiler, dip pen lithography.
|FBG (Fundació Bosch i Gimpera) is a foundation integrated and controlled by the Universitat de Barcelona (UB), and it's in charge of the administrative and financial management of European projects at the UB.|
|IBEC (Institute for Bioengineering of Catalonia) is a research institute covering most bioengineering fields, from basic research to medical applications, aiming to act as an international reference in this field. Promoted by the Generalitat de Catalunya (Autonomous Government of Catalonia), this multidisciplinary centre aimed to coordinate the multidisciplinary research activities in biomedical engineering carried out in Catalonia.|
MAIN TASKS WITHIN THE PROJECT
UB will play the role of the project coordinator, watching for its successful delivery according to time and budget, as well as being responsible for the leadership of the design and conception of the integrated device as a starting point for the working plan and carrying out the characterisation of the nanobiosensor using the provided nanotools. The characterisation entails the following research tasks:
- Full analytical testing of the developed nanobiosensors with the specified olfactory receptor specified in WP2.
- In-vitro extensive experiments in physiological solution, with and without the incorporation of a redox probe to monitor the specific receptor-odorant ligand interaction in various conditions, in order to determine the nanobiosensor detection limits.
- Determination of the optimal experimental conditions for working with impedance spectroscopy
- Validation of the bioelectronic nose device using samples, aiming to establish the feasibility and reliability of the nanobiosensors in real conditions.
- Measurements with nanobiosensors with olfactory receptors of interest to determine the optimal measurement conditions
The Nanobioengineering research group is and has been involved in a large number of European projects, both as participant and coordinator, such as ARAKNES, THERAEDGE (FP7), and CELLPROM, SPOTNOSED, ARES, VECTOR (FP6).
Professor of Electronic Instrumentation at the University of Barcelona
Director of the Research Center for Bioelectronics and Nanobioscience
C/ Baldiri Reixac, 13, 08028 Barcelona (Spain)
Tel. +34 934039705
Fax: +34 934037181
Web: http://www.el.ub.es , http://www.ibecbarcelona.eu
Josep Samitier is Full Professor for Electronic Instrumentation at the Electronic Department University of Barcelona and director of the Laboratory of Nanobioengineering Reserch. Since April 2008, he is acting chancellor of the University of Barcelona, following his appointment as Innovation and International Research vice-chancellor since May 2005. From 1977 to 1982 he studied Physics at the University of Barcelona. He was research fellow during 1983 and 1984 in the Applied Physics Department of the University of Barcelona in the field of GaAs MESFET Devices and electro-optical characterization of III-V semiconductors. From February 1984 to June 1985 he was visiting research fellow at the "Laboratoire D'Electronique Philips, LEP, Paris, France”. In the last ten years, Prof. Samitier has participated in several European research projects concerning integrated microsystems based on silicon technology. He also has been a member of the EU FP6 Nano2Life Network of Excellence, and has an extensive experience in management and leadership of large collaborative projects. He has worked as consultant for industries in the field of smart sensors. Among other honours and responsabilities, Prof. Samitier is member of the international committee of the Int. Society for BioMEMS and Nanotechnology (ISBBN) and of the editorial board of the Journal of Nanoscience and Nanotechnology.
Gabriel Gomila graduated in Physics in 1993 and received the Ph.D degree in Physics in 1997, both at the University of Barcelona (UB). In 1998 he worked as an assistant professor at the UB. From 1999 to 2000 he was a post-doc researcher at the University of Lecce (Italy) and at the University of Montpellier II (France). In 2001 he was visiting professor at the UPC. At the end of 2001, he joined the University of Barcelona, as a researcher within the Spanish Ramon y Cajal Program. Since 2005 is Associate Professor at the Electronics Department (UB). Dr. Gabriel Gomila is the leader of the BioNanoCharacterisation & Manipulation group at the Laboratory of NanoBioEngineering. The group focuses its research activities on Atomic Force Microscopy (AFM) for the study of biological materials, with particular interest to their electrical properties. He is author of more than 30 papers on international peer reviewed journals and has already been PI of two national research projects and has had management responsibilities in other National and European Projects.